GLP-1的音標為[gl?p ?z 1],基本翻譯為“GLP-1”。速記技巧為:GLP(基因型)1(胰島素分泌激素)。
GLP-1的英文詞源是Glucagon-like peptide 1,它是一種由腸道L細胞分泌的激素。其名稱中的“GLP”代表“胰高血糖素樣肽”,而“1”則表示其在生物體內的特定作用部位。
GLP-1的變化形式主要涉及到其與蛋白質的結合形式,以及在體內被降解和代謝的形式。其中一種重要的變化形式是GLP-1的二聚體形式,它是由兩個GLP-1分子通過非共價鍵形成的。這種二聚體形式在體內具有較高的穩定性,并可能具有不同的生物活性。
相關單詞包括:
1. GLP-2:一種與GLP-1具有相似功能的激素,主要在回腸和結腸中分泌。
2. DPP-4:一種酶,能夠降解GLP-1和其他一些肽激素,使其失去生物活性。
3. GIP:一種與GLP-1協同作用的激素,主要在胃和十二指腸中分泌。
4. Pro-GLP-1:GLP-1的前體物質。
5. Exendins:一種在胰島β細胞中分泌的激素家族,與GLP-1具有相似的作用機制。
6. Long-acting GLP-1 receptor agonists (LAGMs):長效GLP-1受體激動劑,一種用于治療糖尿病的藥物形式。
7. GLP-1 receptor antagonists:GLP-1受體拮抗劑,一種潛在的治療糖尿病的藥物形式。
8. GLP-1類似物:一種人工合成的類似GLP-1的肽激素。
9. GLP-1 deficiency:GLP-1缺乏癥,一種罕見的疾病,導致患者無法產生足夠的GLP-1激素。
10. GLP-1 resistance:GLP-1抵抗性,指機體對GLP-1激素的反應性降低。
GLP-1常用短語:
1. GLP-1 receptor激動劑
2. GLP-1類似物
3. GLP-1分泌
4. GLP-1受體激動效應
5. GLP-1受體拮抗劑
6. GLP-1分泌調節
7. GLP-1的生理作用
雙語例句:
1. The use of GLP-1 receptor agonists has been shown to improve diabetes management.
2. The development of GLP-1 analogues has opened up new avenues for the treatment of diabetes.
3. The regulation of GLP-1 secretion is crucial for maintaining healthy glucose levels.
4. The physiological effects of GLP-1 are mediated through its action on the pancreas and brain.
5. The use of GLP-1 receptor antagonists has been studied for the treatment of obesity and gastrointestinal disorders.
6. The role of GLP-1 in maintaining pancreatic function and glucose homeostasis is well established.
7. GLP-1 is a key hormone that regulates appetite and satiety, and its deficiency is associated with diabetes and obesity.
英文小作文:
The Glucagon-like Peptide 1 (GLP-1) hormone plays a crucial role in maintaining glucose homeostasis in the body. It is released by the pancreas in response to meals and promotes the growth of pancreatic cells, leading to increased insulin production and decreased glucose levels. However, the hormone is rapidly degraded by enzymes in the body, making it difficult to maintain effective levels for long periods of time. Therefore, researchers have developed various forms of GLP-1 receptor agonists and analogues that can bind to the receptor more effectively and sustain its effects for longer periods of time. These medications have been shown to improve diabetes management and are currently being studied for the treatment of obesity and other gastrointestinal disorders. Understanding the role of GLP-1 in maintaining glucose homeostasis and developing effective medications to target its effects are critical for improving the health and wellbeing of individuals with diabetes and other related conditions.
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